LITTLE KNOWN FACTS ABOUT (+)-JQ-1 MECHANISM OF ACTION.

In fact, TERT phosphorylation has become proven to be required for telomerase activation. b Outcome of BETi on telomere regulation. BETi compete with acetylated histones for the binding within the BRD4 bromodomains releasing BRD4 from small telomere, destabilizing telomere safety complex Group and cutting down Telomerase activity. The progressive s